[Influence of the velocity of meal ingestion on postprandial glycemia].

To assess the influence of the velocity of meal ingestion on postprandial glycemia, 10 healthy volunteers and 10 patients with non-insulin-dependent diabetes mellitus (NIDDM) were studied. All the subjects had two identical meals (1980 J, carbohydrate 37%, proteins 23%, lipids 40%) on different days. One meal was ingested in 10 minutes (fast ingestion) while the other was ingested in 20 minutes (slow ingestion). Glucose serum levels were measured immediately before the meal and throughout the following 180 minutes. In NIDDM patients, serum glucose levels from 30 to 90 minutes were significantly (p < 0.05) higher after fast ingestion than after the slow intake. Area under the glucose curve (AUC) and maximal peak of serum glucose concentrations (MP) showed also higher values with fast intake: AUC was of 13 +/- 2.4 and 11.3 +/- 2.9 mmol/ L/h (X +/- SD) (p < 0.05), MP 15.8 +/- 4.3 and 12.9 +/- 2.6 mmol/L (p < 0.05) with fast and slow ingestion respectively. No differences in serum glucose levels between test were noticed in healthy subjects. Slow meal ingestion might be a dietary recommendation in patients with NIDDM.