Heart transplant rejection treated with plasmapheresis.
J Partanen, Nieminen Ms, Leena Anneli Krogerus, A L Harjula, Sari Mattila
Abstract
J Partanen, Nieminen Ms, Leena Anneli Krogerus, A L Harjula, Sari Mattila
Abstract
The vascular element of a mixed type of rejection after orthotopic heart transplantation did not respond to steroid therapy in a 30-year-old man. Plasmapheresis was associated with the resolution of the clinical signs of rejection and the microscopic changes of vasculitis in the biopsy specimen. This case suggests that plasmapheresis may be useful in the treatment of acute vascular rejection in heart transplantation.
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The vascular element of a mixed type of rejection after orthotopic heart transplantation did not respond to steroid therapy in a 30-year-old man. Plasmapheresis was associated with the resolution of the clinical signs of rejection and the microscopic changes of vasculitis in the biopsy specimen. This case suggests that plasmapheresis may be useful in the treatment of acute vascular rejection in heart transplantation.
Key concepts: Plasmapheresis, Medicine, Heart transplantation, Vasculitis, Transplantation, Biopsy, Cardiology, Surgery