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HYPOALGESIC EFFECT OF LASER PHOTOBIOSTIMULATION SHOWN BY RAT TAIL FLICK TEST

Rex N. Ponnudurai, Vlasta K. Zbuzek, Wen-Jun Wu

Open publisher page 29 citations

Abstract

We demonstrated a 50% increase in pain threshold following laser photobiostimulation (LPBS), employing rat tail-flick test. Helium-neon laser (1 mW) of three different pulsing frequencies (4, 60, and 200 Hz) was applied on tail low resistance point for 15 seconds and tail-flick latencies were measured 30 minutes, 1 hour, 24 hours, 48 hours and 7 days later. LPBS of 4 Hz produced hypoalgesia of rapid onset and short duration while the response to 60 Hz was delayed and lasted longer. LPBS of 200 Hz did not produce any hypoalgesia.

About this research paper

What this paper is about

We demonstrated a 50% increase in pain threshold following laser photobiostimulation (LPBS), employing rat tail-flick test. Helium-neon laser (1 mW) of three different pulsing frequencies (4, 60, and 200 Hz) was applied on tail low resistance point for 15 seconds and tail-flick latencies were measured 30 minutes, 1 hour, 24 hours, 48 hours and 7 days later. LPBS of 4 Hz produced hypoalgesia of rapid onset and short duration while the response to 60 Hz was delayed and lasted longer. LPBS of 200 Hz did not produce any hypoalgesia.

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OpenAlex reports 29 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

We demonstrated a 50% increase in pain threshold following laser photobiostimulation (LPBS), employing rat tail-flick test. Helium-neon laser (1 mW) of three different pulsing frequencies (4, 60, and 200 Hz) was applied on tail low resistance point for 15 seconds and tail-flick latencies were measured 30 minutes, 1 hour, 24 hours, 48 hours and 7 days later. LPBS of 4 Hz produced hypoalgesia of rapid onset and short duration while the response to 60 Hz was delayed and lasted longer. LPBS of 200 Hz did not produce any hypoalgesia.

Key concepts: Hypoalgesia, Tail flick test, Threshold of pain, Anesthesia, Medicine, Chemistry, Hyperalgesia, Internal medicine

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