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1975•Acta Dermato VenereologicaOpen access

Deposits of immunoglobulins and complement in the dermoepidermal junction of patients with anaphylactoid purpura

Susanne Ullman, P Halberg, Roni Nielsen, Finn Stener Jørgensen, JT. Balslov

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Abstract

Skin biopsies from 3 patients with anaphylactoid purpura examined by an immunofluorescence technique revealed deposits of immunoglobulins, complement C3, and fibrinogen in the dermo-epidermal junction and in vessel walls of clinically involved as well as uninvolved skin. The deposits in the dermo-epidermal junction are similar to those seen in the skin of patients with systemic lupus erythematosus.

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Skin biopsies from 3 patients with anaphylactoid purpura examined by an immunofluorescence technique revealed deposits of immunoglobulins, complement C3, and fibrinogen in the dermo-epidermal junction and in vessel walls of clinically involved as well as uninvolved skin. The deposits in the dermo-epidermal junction are similar to those seen in the skin of patients with systemic lupus erythematosus.

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Available abstract

Skin biopsies from 3 patients with anaphylactoid purpura examined by an immunofluorescence technique revealed deposits of immunoglobulins, complement C3, and fibrinogen in the dermo-epidermal junction and in vessel walls of clinically involved as well as uninvolved skin. The deposits in the dermo-epidermal junction are similar to those seen in the skin of patients with systemic lupus erythematosus.

Key concepts: Dermoepidermal junction, Purpura (gastropod), Medicine, Fibrinogen, Immunofluorescence, Antibody, Dermatology, Complement system

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