2016Chemical CommunicationsRequires access

Comparison of N-acetylcysteine and cysteine in their ability to replenish intracellular cysteine by a specific fluorescent probe

Xinyuan He, Xiao‐Feng Wu, Wen Shi, Huimin Ma

Open publisher page 39 citations

Abstract

A specific fluorescent probe, designed by a substitution-rearrangement mechanism, can discriminate cysteine from other thiols. Using this probe, N-acetylcysteine is revealed to be superior to cysteine to replenish intracellular cysteine in cells.

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What this paper is about

A specific fluorescent probe, designed by a substitution-rearrangement mechanism, can discriminate cysteine from other thiols. Using this probe, N-acetylcysteine is revealed to be superior to cysteine to replenish intracellular cysteine in cells.

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Available abstract

A specific fluorescent probe, designed by a substitution-rearrangement mechanism, can discriminate cysteine from other thiols. Using this probe, N-acetylcysteine is revealed to be superior to cysteine to replenish intracellular cysteine in cells.

Key concepts: Acetylcysteine, Cysteine, Intracellular, Fluorescence, Chemistry, Biochemistry, Enzyme, Antioxidant

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