[Treatment with vitamin D metabolites for rickets/osteomalacia].
Yasuhiro Takeuchi
Abstract
Yasuhiro Takeuchi
Abstract
Rickets and osteomalacia is a metabolic bone disease due to a mineralization defect as principal pathophysiology. Since a variety of disorders cause insufficient mineralization of bone, treatment specific to each disorder should be applied to a patient with rickets/osteomalacia. Clinical consensus for medical treatment for rickets/osteomalacia is overviewed in this manuscript. Vitamin D as an anti-rachitic factor and its metabolites play a pivotal role for treatment of patients with rickets/osteomaracia.
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Rickets and osteomalacia is a metabolic bone disease due to a mineralization defect as principal pathophysiology. Since a variety of disorders cause insufficient mineralization of bone, treatment specific to each disorder should be applied to a patient with rickets/osteomalacia. Clinical consensus for medical treatment for rickets/osteomalacia is overviewed in this manuscript. Vitamin D as an anti-rachitic factor and its metabolites play a pivotal role for treatment of patients with rickets/osteomaracia.
Key concepts: Osteomalacia, Rickets, Vitamin D and neurology, Medicine, Metabolic bone disease, vitamin D deficiency, Internal medicine, Endocrinology