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The effect of thyroidectomy and thyroxine on the reactivity of rat diaphragm muscle to electrical stimulation in vitro.

Adeniyi Ko, Ogunkeye Oo, Solomon S. Senok, Udoh Fu

Abstract

The effect of thyroidectomy and thyroxine on the reactivity of diaphragm muscle to electrical stimulation was studied in adult albino Wistar rats. Thyroidectomy significantly affected the contractility of the diaphragm muscle. The result shows that thyroidectomy predisposes the muscle of the diaphragm to fatigue.

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Key concepts: Diaphragm (acoustics), Diaphragm muscle, Thyroidectomy, Contractility, Stimulation, Internal medicine, Endocrinology, Thyroid