ScholarLens Back to search
1995•Dalian Institute of Chemical Physics, CAS Institutional RepositoryRequires access

SEPARATION OF ENANTIOMERS OF DRUGS BY CAPILLARY ELECTROPHORESIS .1. GAMMA-CYCLODEXTRIN AS CHIRAL SOLVATING AGENT

Bernhard Koppenhoefer, Ulrich Epperlein, Christian Buchberger, Yb Ji, YY Chen, BC Lin

Open publisher page 2 citations

Abstract

Enantiomer separation was studied for a set of 57 chiral drugs. With gamma-cyclodextrin as chiral solvating agent in capillary zone electrophoresis, seven enantiomeric pairs could be separated without recoursing to an optimization procedure. Possible interaction mechanisms between selector and selectand molecules are briefly discussed.

About this research paper

What this paper is about

Enantiomer separation was studied for a set of 57 chiral drugs. With gamma-cyclodextrin as chiral solvating agent in capillary zone electrophoresis, seven enantiomeric pairs could be separated without recoursing to an optimization procedure. Possible interaction mechanisms between selector and selectand molecules are briefly discussed.

Why it matters

OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Enantiomer separation was studied for a set of 57 chiral drugs. With gamma-cyclodextrin as chiral solvating agent in capillary zone electrophoresis, seven enantiomeric pairs could be separated without recoursing to an optimization procedure. Possible interaction mechanisms between selector and selectand molecules are briefly discussed.

Key concepts: Enantiomer, Capillary electrophoresis, Cyclodextrin, Chemistry, Chromatography, Chiral derivatizing agent, Combinatorial chemistry, Molecule

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
SEPARATION OF ENANTIOMERS OF DRUGS BY CAPILLARY ELECTROPHORESIS .1. GAMMA-CYCLODEXTRIN AS CHIRAL SOLVATING AGENT — Research Paper | ScholarLens