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The alkaloids of Strychnos dolichothyrsa.

Robert Verpoorte, Svendsen Ab

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Abstract

In the stem bark of Strychnos dolichothyrsa Gilg ex Onochie et Hepper (Loganiaceae) the following alkaloids were found: bisnor-dihydrotoxiferine, bisnor-C-curarine, bisnor-dihydrotoxiferine N-oxide and bisnor-dihydrotoxiferine di-N-oxide. Tentatively, two alkaloids were identified as bisnor-C-alkaloid D and 18-deoxy Wieland-Gumlich aldehyde. Bisnor-dihydrotoxiferine seems to give dichlorometho compounds and N-oxides easily, analogous with strychnine and brucine.

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What this paper is about

In the stem bark of Strychnos dolichothyrsa Gilg ex Onochie et Hepper (Loganiaceae) the following alkaloids were found: bisnor-dihydrotoxiferine, bisnor-C-curarine, bisnor-dihydrotoxiferine N-oxide and bisnor-dihydrotoxiferine di-N-oxide. Tentatively, two alkaloids were identified as bisnor-C-alkaloid D and 18-deoxy Wieland-Gumlich aldehyde. Bisnor-dihydrotoxiferine seems to give dichlorometho compounds and N-oxides easily, analogous with strychnine and brucine.

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Available abstract

In the stem bark of Strychnos dolichothyrsa Gilg ex Onochie et Hepper (Loganiaceae) the following alkaloids were found: bisnor-dihydrotoxiferine, bisnor-C-curarine, bisnor-dihydrotoxiferine N-oxide and bisnor-dihydrotoxiferine di-N-oxide. Tentatively, two alkaloids were identified as bisnor-C-alkaloid D and 18-deoxy Wieland-Gumlich aldehyde. Bisnor-dihydrotoxiferine seems to give dichlorometho compounds and N-oxides easily, analogous with strychnine and brucine.

Key concepts: Brucine, Strychnos, Strychnine, Alkaloid, Chemistry, Stereochemistry, Biochemistry

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