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[A case report--a patient with gingiva carcinoma showing complete remission after combination chemotherapy with nedaplatin and 5-fluorouracil].

Masanori Nishikawa, Yoshihiko Tsuzaki, Kazuya Maoka, Takehito Nishida, Kozo Sakamoto, Gaku Yamamoto

Abstract

We report a patient showing a complete remission after combination chemotherapy with nedaplatin and 5-fluorouracil (5-FU). A 63-year-old man was admitted to our hospital for advanced carcinoma of gingiva. 5-FU was administered at a dose of 1,000 mg/body (700 mg/m2) by continuous infusion for 120 hours on days 1 to 5. Nedaplatin was administered at a dose of 140 mg/body (90 mg/m2) by drip infusion for 120 minutes on day 5. This combination chemotherapy resulted in a complete remission of the tumor after 2 weeks. There has been no sign of recurrence for 6 months after the chemotherapy.

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Key concepts: Nedaplatin, Fluorouracil, Medicine, Chemotherapy, Complete remission, Carcinoma, Combination chemotherapy, Surgery