Клинико-морфологические особенности хронического гастрита вирусно-бактериальной этиологии

The article presents data showing a significant difference in the cytological composition of inflammatory infiltrates in chronic gastritis of different etiology: bacterial (H. Pylori), virus (EBV ) and viral and bacterial (H. Pylori + EBV). In particular, patients with HP infection and EBV, inactive gastritis was rarely diagnosed (7.1% and 58.3 %, p <0.01) and more pronounced neutrophilic infiltration was determined (57.1% and 16.7 %, p < 0.05) significantly more prevalent were microerosions (50 % and 8.4 %, p <0.05). In herpetic infection were detected significantly more plasma cells per 100 cells in infiltrates of mucosa of the stomach´s body (12,7 ± 3,58 and 5,2 ± 2,5, p <0.001) and antrum (12,43 ± 4,18 and 4,0 ± 2,0, p < 0.001) eosinophiles were more prevalent in infiltrates of mucosa of the stomach´s body ( 96.4 % and 2.0 %, p <0.001) and antrum (92.9 % and 0%, p < 0.001). In addition, processes such as hyperplasy of parietal cells, hyperplasia of foveolar epithelium of the mucous membrane of the stomach body were less likely; pronounced changes of regenerative foveolar mucosal epithelium of the body and antrum of the stomach rarely occured; regenerative changes in the cervical epithelium of the mucous membrane of the body and antrum of the stomach were often absent; marked regenerative changes of the cervical mucosal epithelium of the body, antrum were seldom; regeneration of mucosal epithelium lining the bottom of the gastric body were often absent; intestinal metaplasy in the stomach´s body were rarely detected, stromal fibrosis antrum was rarely diagnosed.