1977PubMedRequires access

[Transferrin in various hematological syndrome].

M Gepner-Woźniewska, E Sitarska, W. Kluciński, L Konopka, S Roszkowski

Open publisher page 0 citations

Abstract

In 100 patients with various haematological syndromes and in 22 healthy subjects serum transferrin was determined by the method of radial immunodiffusion of Mancini. The results were correlated with total iron-binding capacity, iron concentration, beta1 globulin and albumin levels. A statistically significant rise in serum transferrin concentration was demonstrated only in patients with sideropenic anaemia. In the remaining groups of patients transferrin concentration was decreased without regard to associated disturbances of iron metabolism and iron level. The comparison of the total iron-binding capacity with transferrin level determined by radial immunodiffusion may suggest presence of iron-binding proteins other than transferrin.

About this research paper

What this paper is about

In 100 patients with various haematological syndromes and in 22 healthy subjects serum transferrin was determined by the method of radial immunodiffusion of Mancini. The results were correlated with total iron-binding capacity, iron concentration, beta1 globulin and albumin levels. A statistically significant rise in serum transferrin concentration was demonstrated only in patients with sideropenic anaemia. In the remaining groups of patients transferrin concentration was decreased without regard to associated disturbances of iron metabolism and iron level. The comparison of the total iron-binding capacity with transferrin level determined by radial immunodiffusion may suggest presence of iron-binding proteins other than transferrin.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

In 100 patients with various haematological syndromes and in 22 healthy subjects serum transferrin was determined by the method of radial immunodiffusion of Mancini. The results were correlated with total iron-binding capacity, iron concentration, beta1 globulin and albumin levels. A statistically significant rise in serum transferrin concentration was demonstrated only in patients with sideropenic anaemia. In the remaining groups of patients transferrin concentration was decreased without regard to associated disturbances of iron metabolism and iron level. The comparison of the total iron-binding capacity with transferrin level determined by radial immunodiffusion may suggest presence of iron-binding proteins other than transferrin.

Key concepts: Transferrin, Radial immunodiffusion, Albumin, Immunodiffusion, Serum iron, Globulin, Chemistry, Internal medicine

Related papers

Back to paper searchBrowse research topicsOriginal source
[Transferrin in various hematological syndrome]. — Research Paper | ScholarLens