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[Immunohistochemical study of 20 synovial sarcomas in children].

Xavier Sastre‐Garau, J Bosq, C Carlu, F Flamant, Caillaud Jm

Abstract

Histopathologic study of 20 cases of synovial sarcoma (S.S.) in children has been conducted to evaluate the usefulness of immunohistochemistry in the diagnostic assessment of this tumor. Two of the 6 antibodies studied have been found to be the most informative: staining for keratin and vimentin proteins has been observed in most cases, outlining the epithelial and sarcomatous components of this tumor. The results are in accordance with those already described for S.S. in adults. The presence of cytokeratins in S.S. is discordant with classical histogenetic conceptions.

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Available abstract

Key concepts: Immunohistochemistry, Synovial sarcoma, Vimentin, Pathology, Keratin, Sarcoma, Staining, Medicine