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[Study of toxicity on male reproductive system of mice induced by SO2 inhalation].

Bo Zhang, Chengyun Liu, Ziqiang Meng

Abstract

OBJECTIVE: In this paper, toxicity of SO2 on male reproductive system of mice was studied. METHODS: 40 mice were divided to 4 groups (10/group): a group for control, the other 3 groups for SO2 inhalation (28, 56, 112mg/m3), 4h/d, 7d. RESULTS: The activities of GST and G-6-PD, as well as the content of GSH decreased significantly with SO2 increased. The content of MDA increased evidently with SO2 increased. CONCLUSION: SO2 can influence GSH oxidation-deoxidation system and cause DNA damage in male reproductive system of mice.

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Key concepts: Inhalation, Reproductive system, Reproductive toxicity, Male reproductive system, Toxicity, Glutathione, Oxidative damage, Andrology