Gas gangrene and hyperbaric oxygen.

From 1964-1987 we have examined 31 patients suspected to have gaseous gangrene. The diagnosis was confirmed 13 times on clinical and microbiologic grounds. 61% of the patients underwent amputation, 28% died. On the basis of this experience we have tried to define a therapeutic attitude. We recommend an adequate debridement, i.e. the removal of necrotic tissue and drainage of the wound, microbiological investigations and the administration of antibiotics before hyperbaric oxygen treatment is begun (2-3 treatments over 3 days).