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Quantitation of circulating hematopoietic progenitor cells early after transplantation.

Wolfgang Gebauer, E Fallgren Gebauer, C Corbes, Friedrich Schunter

Abstract

By multicolor flow cytometry CD34 positive blood progenitor cells (BPC) were determined by standard procedures before and after reinfusion. Measurements of circulating progenitor cells after transplantation lead to cell numbers that are considered together with reconstitution potential, especially with the number of transfused apheresis platelet concentrates after transplantation. Decreased concentrations of CD34 positive cells are associated with an increased frequency of platelet transfusions after transplantation.

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Key concepts: Apheresis, Progenitor cell, CD34, Haematopoiesis, Flow cytometry, Transplantation, Platelet, Progenitor