2012PubMedRequires access

Add-on diagnostic tool for allergic contact dermatitis: the strip patch test.

Schapoor Hessam, P Altmeyer, Heinrich Dickel

Open publisher page 1 citations

Abstract

The "conventional" patch test (PT) is considered to be the "gold standard" in diagnosing allergic contact dermatitis. However, the method of patch testing has repeatedly been criticized for its limited diagnostic accuracy and it is therefore by no means uniformly accepted as a reliable test method. Basic idea of the "strip" patch test (SPT), a modification by repeated tape stripping prior to patch testing, is to increase the quantity of allergen reaching the deeper epidermal cell layers and, thus, to increase the test sensitivity. The SPT according to our proposed standardized protocol is promising to improve diagnosis of allergic contact dermatitis which is demonstrated exemplary in the field of occupational contact dermatitis.

About this research paper

What this paper is about

The "conventional" patch test (PT) is considered to be the "gold standard" in diagnosing allergic contact dermatitis. However, the method of patch testing has repeatedly been criticized for its limited diagnostic accuracy and it is therefore by no means uniformly accepted as a reliable test method. Basic idea of the "strip" patch test (SPT), a modification by repeated tape stripping prior to patch testing, is to increase the quantity of allergen reaching the deeper epidermal cell layers and, thus, to increase the test sensitivity. The SPT according to our proposed standardized protocol is promising to improve diagnosis of allergic contact dermatitis which is demonstrated exemplary in the field of occupational contact dermatitis.

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Available abstract

The "conventional" patch test (PT) is considered to be the "gold standard" in diagnosing allergic contact dermatitis. However, the method of patch testing has repeatedly been criticized for its limited diagnostic accuracy and it is therefore by no means uniformly accepted as a reliable test method. Basic idea of the "strip" patch test (SPT), a modification by repeated tape stripping prior to patch testing, is to increase the quantity of allergen reaching the deeper epidermal cell layers and, thus, to increase the test sensitivity. The SPT according to our proposed standardized protocol is promising to improve diagnosis of allergic contact dermatitis which is demonstrated exemplary in the field of occupational contact dermatitis.

Key concepts: Patch test, Patch testing, Allergic contact dermatitis, Contact dermatitis, Dermatology, Gold standard (test), Allergen, Medicine

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