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[Oxidative and respiratory properties of isolated human kidney mitochondria].

Klaus Jung, C Reinholdt

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Abstract

The oxidative and respiratory properties of isolated human renal mitochondria are characterized on the basis of the respiratory rates under defined conditions (active and decoupled respiration as well as respiration in rest) with the help of the respiratory control index and the ADP/O quotient. In comparison to the renal mitochondria of the rats the balances for the substrates succinate and glutamate/malate are three- to fourfold smaller.

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The oxidative and respiratory properties of isolated human renal mitochondria are characterized on the basis of the respiratory rates under defined conditions (active and decoupled respiration as well as respiration in rest) with the help of the respiratory control index and the ADP/O quotient. In comparison to the renal mitochondria of the rats the balances for the substrates succinate and glutamate/malate are three- to fourfold smaller.

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Available abstract

The oxidative and respiratory properties of isolated human renal mitochondria are characterized on the basis of the respiratory rates under defined conditions (active and decoupled respiration as well as respiration in rest) with the help of the respiratory control index and the ADP/O quotient. In comparison to the renal mitochondria of the rats the balances for the substrates succinate and glutamate/malate are three- to fourfold smaller.

Key concepts: Oxidative phosphorylation, Mitochondrion, Respiration, Respiratory system, Respiratory quotient, Glutamate receptor, Kidney, Cellular respiration

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