ScholarLens Back to search
1991•Journal of ChemotherapyRequires access

β-Lactamase Induction Antagonizes β-Lactam Susceptibilities inCitrobacter diversusandEnterobacter cloacaeClinical Isolates

B Oliva, Tea Taraborelli, Nicola Franceschini, Gianfranco Amicosante

Open publisher page 0 citations

Abstract

Inducible beta-lactamases were obtained after exposure to several beta-lactams in clinical isolates of Enterobacter cloacae and Citrobacter diversus. Enzyme production was related to the inducer and medium composition. beta-lactamase is able to inactivate only labile compounds, thus generating minimum inhibitory concentrations higher than in the absence of the inducer; imipenem susceptibilities usually were not changed.

About this research paper

What this paper is about

Inducible beta-lactamases were obtained after exposure to several beta-lactams in clinical isolates of Enterobacter cloacae and Citrobacter diversus. Enzyme production was related to the inducer and medium composition. beta-lactamase is able to inactivate only labile compounds, thus generating minimum inhibitory concentrations higher than in the absence of the inducer; imipenem susceptibilities usually were not changed.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Inducible beta-lactamases were obtained after exposure to several beta-lactams in clinical isolates of Enterobacter cloacae and Citrobacter diversus. Enzyme production was related to the inducer and medium composition. beta-lactamase is able to inactivate only labile compounds, thus generating minimum inhibitory concentrations higher than in the absence of the inducer; imipenem susceptibilities usually were not changed.

Key concepts: Enterobacter cloacae, Citrobacter, Imipenem, Inducer, Microbiology, Enterobacter, Enterobacteriaceae, Enzyme inducer

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
β-Lactamase Induction Antagonizes β-Lactam Susceptibilities inCitrobacter diversusandEnterobacter cloacaeClinical Isolates — Research Paper | ScholarLens