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[Frequency and distribution of variable-number tandem repeats in the genome of Aspergillus niculans].

Chengyun Li, Jinbin Li, Xiaogang Zhou, Shaosong Zhang, Minghui Xu

Abstract

A total of 30.1 Mb of publicly available DNA sequence in Aspergillus niculans was researched for mono- to hexanucleotide variable-number tandem repeat (VNTR) to determine its type, size and frequency. A total of 4 837 VNTRs were observed in whole genomic DNA sequence with criteria of VNTR length > 15 bp and 80% matches. Considering all six classes of VNTRs, they occur on average about once every 6.2 kb for mono- to hexanucleotide in genomic DNA. The most abundance variable-number tandem repeat is pentanucleotide repeats; the number was 1 386, followed by hexanucleotide and trinucleotide repeats, the number was 1 228 and 1 199 respectively. The least abundance is dinucleotide repeat, only 144 tracts.

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Key concepts: Variable number tandem repeat, Biology, Tandem repeat, Genetics, Direct repeat, Repeated sequence, Genome, genomic DNA