Adenomatoid tumors. Immunohistochemical study and histogenesis.
Mariano Urdiales-Viedma, S Martos-Padilla, Trinidad Caballero-Morales
Abstract
Mariano Urdiales-Viedma, S Martos-Padilla, Trinidad Caballero-Morales
Abstract
Four testicular adenomatoid tumors were studied by immunohistochemistry, using the following antibodies to cytokeratin, epithelial membrane antigen, carcinoembryonic antigen, and factor VIII-related antigen. Cytokeratin and epithelial membrane antigen demonstrated a different pattern of positive immunostaining while carcinoembryonic antigen and factor VIII-related antigen proved constantly negative. Our findings support a mesothelial origin for adenomatoid tumors.
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Four testicular adenomatoid tumors were studied by immunohistochemistry, using the following antibodies to cytokeratin, epithelial membrane antigen, carcinoembryonic antigen, and factor VIII-related antigen. Cytokeratin and epithelial membrane antigen demonstrated a different pattern of positive immunostaining while carcinoembryonic antigen and factor VIII-related antigen proved constantly negative. Our findings support a mesothelial origin for adenomatoid tumors.
Key concepts: Carcinoembryonic antigen, Immunohistochemistry, Histogenesis, Cytokeratin, Pathology, Immunostaining, Adenomatoid tumor, Antigen