2011•PubMedRequires access

[Intracranial aneurysms in childhood and adolescence].

Jiantao Liang, Yuhai Bao, Hongqi Zhang, Feng Ling

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Abstract

OBJECTIVE: To assess the radiological characteristics and therapeutic strategies of intracranial aneurysms in childhood and adolescence. METHODS: From our dedicated aneurysmal patient databank, the investigators reviewed 39 consecutive children and adolescents with 44 intracranial aneurysms. There were 24 boys and 15 girls. RESULTS: Twenty-two patients underwent endovascular treatment. Among them, 8 patients received microsurgical therapy. Aneurysms became spontaneously thrombosed before therapy in 3 patients. One patient died pre-operatively from a re-rupture of aneurysm. And 5 cases were not treated at all. CONCLUSION: Intracranial aneurysms in childhood and adolescence have many clinical and radiological characteristics: (1) remarkable male predominance; (2) middle cerebral artery is the most common site for aneurysms; (3) there is a high prevalence of giant, traumatic, dissecting and fusiform aneurysms; (4) both microsurgical approaches and endovascular treatment were effective. For some giant complex intracranial aneurysms, parent arterial occlusion or EC-IC (extracranial-intracranial) bypass is the best therapeutic choice. A majority of patients may have favorable outcomes.

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OBJECTIVE: To assess the radiological characteristics and therapeutic strategies of intracranial aneurysms in childhood and adolescence. METHODS: From our dedicated aneurysmal patient databank, the investigators reviewed 39 consecutive children and adolescents with 44 intracranial aneurysms. There were 24 boys and 15 girls. RESULTS: Twenty-two patients underwent endovascular treatment. Among them, 8 patients received microsurgical therapy. Aneurysms became spontaneously thrombosed before therapy in 3 patients. One patient died pre-operatively from a re-rupture of aneurysm. And 5 cases were not treated at all. CONCLUSION: Intracranial aneurysms in childhood and adolescence have many clinical and radiological characteristics: (1) remarkable male predominance; (2) middle cerebral artery is the most common site for aneurysms; (3) there is a high prevalence of giant, traumatic, dissecting and fusiform aneurysms; (4) both microsurgical approaches and endovascular treatment were effective. For some giant complex intracranial aneurysms, parent arterial occlusion or EC-IC (extracranial-intracranial) bypass is the best therapeutic choice. A majority of patients may have favorable outcomes.

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Available abstract

OBJECTIVE: To assess the radiological characteristics and therapeutic strategies of intracranial aneurysms in childhood and adolescence. METHODS: From our dedicated aneurysmal patient databank, the investigators reviewed 39 consecutive children and adolescents with 44 intracranial aneurysms. There were 24 boys and 15 girls. RESULTS: Twenty-two patients underwent endovascular treatment. Among them, 8 patients received microsurgical therapy. Aneurysms became spontaneously thrombosed before therapy in 3 patients. One patient died pre-operatively from a re-rupture of aneurysm. And 5 cases were not treated at all. CONCLUSION: Intracranial aneurysms in childhood and adolescence have many clinical and radiological characteristics: (1) remarkable male predominance; (2) middle cerebral artery is the most common site for aneurysms; (3) there is a high prevalence of giant, traumatic, dissecting and fusiform aneurysms; (4) both microsurgical approaches and endovascular treatment were effective. For some giant complex intracranial aneurysms, parent arterial occlusion or EC-IC (extracranial-intracranial) bypass is the best therapeutic choice. A majority of patients may have favorable outcomes.

Key concepts: Medicine, Aneurysm, Radiological weapon, Surgery, Occlusion, Fusiform Aneurysm, Endovascular treatment, Radiology

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