1992•American Journal of Tropical Medicine and HygieneRequires access

Tumor Necrosis Factor in the Malnutrition (Cachexia) of Infection and Cancer

Kevin J. Tracey, Anthony Cerami

Open publisher page 40 citations

Abstract

This review presents a history of tumor necrosis factor, considers the biology of this pleiotropic mediator, and summarizes the evidence that implicates it as a mediator of cachexia.

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What this paper is about

This review presents a history of tumor necrosis factor, considers the biology of this pleiotropic mediator, and summarizes the evidence that implicates it as a mediator of cachexia.

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OpenAlex reports 40 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

This review presents a history of tumor necrosis factor, considers the biology of this pleiotropic mediator, and summarizes the evidence that implicates it as a mediator of cachexia.

Key concepts: Cachexia, Mediator, Cancer cachexia, Malnutrition, Tumor necrosis factor alpha, Tumor necrosis factor α, Cancer, Necrosis

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