1995•PubMedRequires access

[Biological properties and clinical importance of interleukin 1].

Tadeusz Robak

Abstract

The paper presents the molecular biology and biological activity of IL-1 alpha, IL-1 beta and IL-1 receptor antagonist. The role of IL-1 family in pathogenesis of a various disease including myeloid leukemias and other neoplastic diseases, diabetes mellitus, inflammatory diseases, sepsis syndrome and atherosclerosis is presented. Potential therapeutic value of IL-1 and IL-1 receptor antagonist is also discussed.

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Available abstract

Key concepts: Interleukin 1 receptor antagonist, Pathogenesis, Immunology, Diabetes mellitus, Disease, Receptor antagonist, Sepsis, Medicine