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[Transjugular intrahepatic portosystemic shunt: a new therapy for portal hypertension].

R Yamada, Yojiro Koda, Masao Hamuro, Sadanari Hayashi, K Nakamura, Hirohiko Tanihata, Sentaro Kimura, Masahiro Sato

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Abstract

Thirty-five patients with portal hypertension due to liver cirrhosis secondary to chronic viral hepatitis underwent transjuglar intrahepatic portosystemic shunt for the last 3-year period. Shunts were successfully completed in 31 of 35 patients at 89%. Portal vein pressure was markedly reduced on average in the all cases until 6 months after TIPS. The endoscopic findings of varices much improved in 90% of the patients. Long-term patency rates of TIPS were 97% after 4 weeks, 79% after 6 months, 76% after a year and 55% after 2 years, respectively. The authors concluded that TIPS was an effective and reliable means of lowering portal pressure, improving endoscopic findings of varices and controlling of refractory ascites.

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What this paper is about

Thirty-five patients with portal hypertension due to liver cirrhosis secondary to chronic viral hepatitis underwent transjuglar intrahepatic portosystemic shunt for the last 3-year period. Shunts were successfully completed in 31 of 35 patients at 89%. Portal vein pressure was markedly reduced on average in the all cases until 6 months after TIPS. The endoscopic findings of varices much improved in 90% of the patients. Long-term patency rates of TIPS were 97% after 4 weeks, 79% after 6 months, 76% after a year and 55% after 2 years, respectively. The authors concluded that TIPS was an effective and reliable means of lowering portal pressure, improving endoscopic findings of varices and controlling of refractory ascites.

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Available abstract

Thirty-five patients with portal hypertension due to liver cirrhosis secondary to chronic viral hepatitis underwent transjuglar intrahepatic portosystemic shunt for the last 3-year period. Shunts were successfully completed in 31 of 35 patients at 89%. Portal vein pressure was markedly reduced on average in the all cases until 6 months after TIPS. The endoscopic findings of varices much improved in 90% of the patients. Long-term patency rates of TIPS were 97% after 4 weeks, 79% after 6 months, 76% after a year and 55% after 2 years, respectively. The authors concluded that TIPS was an effective and reliable means of lowering portal pressure, improving endoscopic findings of varices and controlling of refractory ascites.

Key concepts: Medicine, Portal hypertension, Transjugular intrahepatic portosystemic shunt, Ascites, Portal venous pressure, Cirrhosis, Varices, Gastroenterology

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[Transjugular intrahepatic portosystemic shunt: a new therapy for portal hypertension]. — Research Paper | ScholarLens