Chiral Separations by Capillary Electrophoresis
Manus M. Rogan, Kevin D. Altria
Abstract
Manus M. Rogan, Kevin D. Altria
Abstract
Many papers have appeared concerning the application of capillary electrophoresis (CE) to the resolution of chiral compounds. Predominantly, separations have been achieved in Free Solution Capillary Electrophoresis (FSCE) employing cyclodextrins (CDs) as chiral selectors. This is because of their ready availability and broad applicability. Chiral resolutions have also been achieved in micellar electrokinetic chromatography (MEKC) through the use of chirally selective micelles. However, the variety of approaches has increased significantly. In this chapter, the use and applicability of these methods are considered. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Many papers have appeared concerning the application of capillary electrophoresis (CE) to the resolution of chiral compounds. Predominantly, separations have been achieved in Free Solution Capillary Electrophoresis (FSCE) employing cyclodextrins (CDs) as chiral selectors. This is because of their ready availability and broad applicability. Chiral resolutions have also been achieved in micellar electrokinetic chromatography (MEKC) through the use of chirally selective micelles. However, the variety of approaches has increased significantly. In this chapter, the use and applicability of these methods are considered. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Key concepts: Micellar electrokinetic chromatography, Capillary electrophoresis, Chromatography, Electrokinetic phenomena, Electrophoresis, Resolution (logic), Chemistry, Capillary action