[Influence of galascorbin on the levels of potassium and sodium in the organs and tissues of guinea pigs in burn disease].

The burn disease is accompanied by considerable disturbances in mineral metabolism, which is manifested in retention of sodium and loss of potassium in tissues and in disturbances in distribution of these ions between cells and intercellular space. This results in an increase in the proportion intracellular sodium/extracellular sodium and a decrease in the proportion intracellular potassium/extracellular potassium. Application of galascorbic acid prevents from both the increase in the total sodium quantity and its intracellular fraction and eliminates such a considerable loss of potassium by tissues.