[An experimental study of the immunogenicity of Pseudomonas aeruginosa vaccines].
Akatova Ns
Abstract
Akatova Ns
Abstract
The author studied comparatively the immunogenicity of the vaccines prepared of 38 virulent Ps. aeruginosa strains belonging to different serological types. It was demonstrated that the immunogenicity of killed vaccines varied within a wide range--from the absoulte protective effect to its complete absence. The culture medium on which the initial culture was grown and the method of its detoxication produced practically no influence on the immunogenicity of the vaccines. Immunogenicity of Ps. aeruginosa vaccines apparently had no relationship with the serological type of the strains.
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The author studied comparatively the immunogenicity of the vaccines prepared of 38 virulent Ps. aeruginosa strains belonging to different serological types. It was demonstrated that the immunogenicity of killed vaccines varied within a wide range--from the absoulte protective effect to its complete absence. The culture medium on which the initial culture was grown and the method of its detoxication produced practically no influence on the immunogenicity of the vaccines. Immunogenicity of Ps. aeruginosa vaccines apparently had no relationship with the serological type of the strains.
Key concepts: Immunogenicity, Serology, Pseudomonas aeruginosa, Microbiology, Virology, Virulence, Biology, Immune system