[Enhancement of drug absorption by iontophoresis and phonophoresis and clinical application].

Concepts of iontophoresis and phonophoresis are described. Main factors regarding iontophoretic transdermal drug delivery of ionized drugs or non-ionized drugs and clinical applications are outlined. Iontophoretic and sonophoretic transdermal drug delivery has some advantages and disadvantages. However, its clinical use for controlled drug delivery corresponding to chronopharmacology will bring more benefit to patients in near future.