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[Usefulness of scintigraphy using 99mTc-MIBI for localization of parathyroid adenoma].

E Leowska, Witold Chudziński, T Tołłoczko, W Graban

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Abstract

Aim of this study was to evaluate the significance of 99mTc-MIBI scintigraphy in detection of parathyroid adenomas in patients with primary and primary recurrent or persistent hyperparathyroidism after surgical treatment. The images of the neck and mediastinum were taken 20 minutes and 2 hours after i.v. injection of the radiopharmaceutic. Result of the scintigraphy was defined as positive when the initial high 99mTc-MIBI uptake persistent in the region of the neck or mediastinum. At this time the radioactivity from thyroid gland declined significantly. Parathyroid adenoma was confirmed by surgery in 10 out of 12 cases diagnosed by scintigraphy. Parathyroid imaging using 99mTc-MIBI is a promising procedure in the preoperative localisation of parathyroid adenomas in patient with hyperparathyroidism.

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What this paper is about

Aim of this study was to evaluate the significance of 99mTc-MIBI scintigraphy in detection of parathyroid adenomas in patients with primary and primary recurrent or persistent hyperparathyroidism after surgical treatment. The images of the neck and mediastinum were taken 20 minutes and 2 hours after i.v. injection of the radiopharmaceutic. Result of the scintigraphy was defined as positive when the initial high 99mTc-MIBI uptake persistent in the region of the neck or mediastinum. At this time the radioactivity from thyroid gland declined significantly. Parathyroid adenoma was confirmed by surgery in 10 out of 12 cases diagnosed by scintigraphy. Parathyroid imaging using 99mTc-MIBI is a promising procedure in the preoperative localisation of parathyroid adenomas in patient with hyperparathyroidism.

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Available abstract

Aim of this study was to evaluate the significance of 99mTc-MIBI scintigraphy in detection of parathyroid adenomas in patients with primary and primary recurrent or persistent hyperparathyroidism after surgical treatment. The images of the neck and mediastinum were taken 20 minutes and 2 hours after i.v. injection of the radiopharmaceutic. Result of the scintigraphy was defined as positive when the initial high 99mTc-MIBI uptake persistent in the region of the neck or mediastinum. At this time the radioactivity from thyroid gland declined significantly. Parathyroid adenoma was confirmed by surgery in 10 out of 12 cases diagnosed by scintigraphy. Parathyroid imaging using 99mTc-MIBI is a promising procedure in the preoperative localisation of parathyroid adenomas in patient with hyperparathyroidism.

Key concepts: Medicine, Primary hyperparathyroidism, Scintigraphy, Mediastinum, Hyperparathyroidism, Adenoma, Parathyroid adenoma, Radiology

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[Usefulness of scintigraphy using 99mTc-MIBI for localization of parathyroid adenoma]. — Research Paper | ScholarLens