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[Dietary protein as a modulator of the activity of enzymes metabolizing xenobiotics. Epoxide hydrolase].

V A Tutel'ian, Kravchenko Lv, E E Kuz'mina

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Abstract

Growing male rats received rations containing 5.18 and 33% of protein during 2 months. In contrast to other microsomal enzymes, epoxide hydrolase activity was maximal in the liver of the animals which received the ration with 5% of protein, and minimal--with 18% of protein. Epoxide hydrolase in the liver of rats that received the rations with 5 and 18% of protein showed equally expressed capacity for induction and activation in vivo and in vitro.

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Growing male rats received rations containing 5.18 and 33% of protein during 2 months. In contrast to other microsomal enzymes, epoxide hydrolase activity was maximal in the liver of the animals which received the ration with 5% of protein, and minimal--with 18% of protein. Epoxide hydrolase in the liver of rats that received the rations with 5 and 18% of protein showed equally expressed capacity for induction and activation in vivo and in vitro.

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Available abstract

Growing male rats received rations containing 5.18 and 33% of protein during 2 months. In contrast to other microsomal enzymes, epoxide hydrolase activity was maximal in the liver of the animals which received the ration with 5% of protein, and minimal--with 18% of protein. Epoxide hydrolase in the liver of rats that received the rations with 5 and 18% of protein showed equally expressed capacity for induction and activation in vivo and in vitro.

Key concepts: Epoxide hydrolase, Epoxide hydrolase 2, Microsomal epoxide hydrolase, Enzyme, Biochemistry, Hydrolase, Chemistry, Xenobiotic

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[Dietary protein as a modulator of the activity of enzymes metabolizing xenobiotics. Epoxide hydrolase]. — Research Paper | ScholarLens