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Diagnostic pitfalls in cerebrospinal fluid cytology.

Masayuki Takeda, King De, Choi Hy, Kazunori Gomi, Lang Wr

Abstract

Four types of cells that may be the source of important diagnostic pitfalls in cerebrospinal fluid cytology are presented: (1) nucleus pulposus cells, (2) keratinized squamous cells from craniopharyngioma and sphenoid sinus carcinoma, (3) reactive leptomeningeal cells and (4) epitheloid cells from sarcoidosis. For each the cellular morphology is described and representative clinical, cytologic and histologic presentations are discussed.

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Key concepts: Medicine, Cerebrospinal fluid, Cytology, Pathology, Craniopharyngioma, Sarcoidosis, Malignant cells, Sinus (botany)