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[Uncomplicated malaria attack in an area with high resistance to chloroquine. 3. The use of second-choice oral drug treatment].

C. Hengy, Franziska Eberle, Pierre Gazin, D. Kouka-Bemba, H. Gélas, Ronan Jambou

Abstract

This study appreciated the efficiency of uncomplicated malaria second line treatment (P. falciparum) in an area with high level of chemoresistance. No therapeutic failure was found with sulfadoxine-pyrimethamine (Fansidar), and mefloquine-sulfadoxine-pyrimethamine (Fansimef), in contrast with a rate of 8% with quinine. The authors discuss the place of these therapeutic, in the treatment of malaria.

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Available abstract

Key concepts: Mefloquine, Malaria, Sulfadoxine, Chloroquine, Quinine, Sulfadoxine/pyrimethamine, Pyrimethamine, Medicine