2000•PubMedRequires access
Prognostic significance of tissue DF3 antigen and CA15-3 tumor marker in primary breast cancer.
Cleanthi Dimas, M Fragos-Plemenos, C. Gennatas, E. Kouskouni, A Kondi-Paphitis
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Abstract
The specific monoclonal antibody, DF3, for breast cancer and the corresponding tumor marker CA15-3 were evaluated in 108 patients with primary cancer of the breast. These antigens correlated poorly with the known prognostic parameters. Elevated CA15-3 serum values were associated with the cytoplasmic distribution of the DF3 antigen in the cell. The DF3 distribution pattern and the CA15-3 serum values had prognostic significance for disease-free interval.