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The Relationship between Plasma Biotin Concentration and Circulating Leucocyte β-Methylcrotonyl-CoA Carboxylase and Propionyl-CoA Carboxylase

K. Bartlett, T. Horsburgh, D. Gompertz

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Abstract

1. A newly developed biotin assay was used to monitor plasma and urinary biotin concentration after the oral administration of biotin. 2. In two normal subjects, leucocyte propionyl-CoA carboxylase and beta-methylcrotonyl-CoA carboxylase were markedly stimulated after the administration of biotin.

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What this paper is about

1. A newly developed biotin assay was used to monitor plasma and urinary biotin concentration after the oral administration of biotin. 2. In two normal subjects, leucocyte propionyl-CoA carboxylase and beta-methylcrotonyl-CoA carboxylase were markedly stimulated after the administration of biotin.

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Available abstract

1. A newly developed biotin assay was used to monitor plasma and urinary biotin concentration after the oral administration of biotin. 2. In two normal subjects, leucocyte propionyl-CoA carboxylase and beta-methylcrotonyl-CoA carboxylase were markedly stimulated after the administration of biotin.

Key concepts: Biotin, Pyruvate carboxylase, Acetyl-CoA carboxylase, Endocrinology, Chemistry, Biochemistry, Internal medicine, Biology

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The Relationship between Plasma Biotin Concentration and Circulating Leucocyte β-Methylcrotonyl-CoA Carboxylase and Propionyl-CoA Carboxylase — Research Paper | ScholarLens