2008PubMedRequires access

[Effects of ethanol on hemostasis].

Wojciech Jelski, Maciej Szmitkowski

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Abstract

Ethanol has multiple effects on hemostasis, affecting platelets, coagulation factors, and the fibrinolytic system. Results in the literature growing evidence is pointing to the following effects of ethanol or its metabolites: partial platelet activation generating poorly functioning platelets, decreased levels of fibrinogen and selected other factors, and increased fibrinolysis. This beneficial effect on hemostasis is likely to contribute to the protective effect of cardiovascular diseases.

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What this paper is about

Ethanol has multiple effects on hemostasis, affecting platelets, coagulation factors, and the fibrinolytic system. Results in the literature growing evidence is pointing to the following effects of ethanol or its metabolites: partial platelet activation generating poorly functioning platelets, decreased levels of fibrinogen and selected other factors, and increased fibrinolysis. This beneficial effect on hemostasis is likely to contribute to the protective effect of cardiovascular diseases.

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Available abstract

Ethanol has multiple effects on hemostasis, affecting platelets, coagulation factors, and the fibrinolytic system. Results in the literature growing evidence is pointing to the following effects of ethanol or its metabolites: partial platelet activation generating poorly functioning platelets, decreased levels of fibrinogen and selected other factors, and increased fibrinolysis. This beneficial effect on hemostasis is likely to contribute to the protective effect of cardiovascular diseases.

Key concepts: Hemostasis, Fibrinolysis, Platelet, Coagulation, Fibrinogen, Ethanol, Platelet aggregation, Platelet activation

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