1981•PubMedRequires access

[Determination of bumadizone, phenylbutazone and oxyphenbutazone in human plasma by high-performance liquid chromatography (author's transl)].

H. Spahn, E. Mutschler

Abstract

HPLC methods are described to determine bumadizone, phenylbutazone and oxyphenbutazone in human plasma. The procedure for the determination of phenylbutazone and oxyphenbutazone is based on a microphase extraction and especially suitable for routine analyses because of its simplicity and rapidity. 0.5 microgram of the compounds per milliliter plasma can easily be determined; the relative standard deviations of the methods are between 0.7 and 4.4% at therapeutic plasma concentrations.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 5 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Oxyphenbutazone, Phenylbutazone, Chromatography, Chemistry, Human plasma, High-performance liquid chromatography, Plasma levels, Extraction (chemistry)