[Pneumocystis pneumonia in patients with immunosuppression other than HIV infection].
Dan Adler, Cécile Chenivesse, Thomas Similowski, Paola M. Soccal
Abstract
Dan Adler, Cécile Chenivesse, Thomas Similowski, Paola M. Soccal
Abstract
Pneumocystis jirovecii is an opportunistic pathogen causing life-threatening pneumonia in immunosuppressed patients. The number of non-HIV immunosuppressed patients at risk for Pneumocystis pneumonia is rapidly growing. In contrast to HIV patients, there are no guidelines for Pneumocystis prophylaxis in other immunocompromised hosts. A detailed analysis of current literature data allowed us hereby to define the type of immunocompromised patients for whom evidence suggests a benefit for PCP prophylaxis.
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Pneumocystis jirovecii is an opportunistic pathogen causing life-threatening pneumonia in immunosuppressed patients. The number of non-HIV immunosuppressed patients at risk for Pneumocystis pneumonia is rapidly growing. In contrast to HIV patients, there are no guidelines for Pneumocystis prophylaxis in other immunocompromised hosts. A detailed analysis of current literature data allowed us hereby to define the type of immunocompromised patients for whom evidence suggests a benefit for PCP prophylaxis.
Key concepts: Immunosuppression, Pneumocystis jirovecii, Pneumocystis pneumonia, Pneumonia, Pneumocystis carinii, Opportunistic infection, Medicine, Immunology