[Domperidone as an anti-emetic in antineoplastic chemotherapy].
U. Caruso, S D'Iddio, E Cravotto, Samantha Pesce, Irene Betti, G. Ruscitto, U Ecari, A M Sabrie
Abstract
U. Caruso, S D'Iddio, E Cravotto, Samantha Pesce, Irene Betti, G. Ruscitto, U Ecari, A M Sabrie
Abstract
The antiemetic effects of domperidone in patients undergoing post-surgical cytostatic treatment for stomach and colorectal carcinoma have been evaluated. The study has been performed on 3 groups of patients treated with domperidone, metoclopramide and placebo respectively. The antiemetic activity of domperidone proved to be better than that of metoclopramide. No side effects were observed in patients treated with domperidone.
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The antiemetic effects of domperidone in patients undergoing post-surgical cytostatic treatment for stomach and colorectal carcinoma have been evaluated. The study has been performed on 3 groups of patients treated with domperidone, metoclopramide and placebo respectively. The antiemetic activity of domperidone proved to be better than that of metoclopramide. No side effects were observed in patients treated with domperidone.
Key concepts: Domperidone, Metoclopramide, Medicine, Antiemetic, Dopamine antagonist, Chemotherapy, Anesthesia, Placebo