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[Domperidone as an anti-emetic in antineoplastic chemotherapy].

U. Caruso, S D'Iddio, E Cravotto, Samantha Pesce, Irene Betti, G. Ruscitto, U Ecari, A M Sabrie

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Abstract

The antiemetic effects of domperidone in patients undergoing post-surgical cytostatic treatment for stomach and colorectal carcinoma have been evaluated. The study has been performed on 3 groups of patients treated with domperidone, metoclopramide and placebo respectively. The antiemetic activity of domperidone proved to be better than that of metoclopramide. No side effects were observed in patients treated with domperidone.

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What this paper is about

The antiemetic effects of domperidone in patients undergoing post-surgical cytostatic treatment for stomach and colorectal carcinoma have been evaluated. The study has been performed on 3 groups of patients treated with domperidone, metoclopramide and placebo respectively. The antiemetic activity of domperidone proved to be better than that of metoclopramide. No side effects were observed in patients treated with domperidone.

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The antiemetic effects of domperidone in patients undergoing post-surgical cytostatic treatment for stomach and colorectal carcinoma have been evaluated. The study has been performed on 3 groups of patients treated with domperidone, metoclopramide and placebo respectively. The antiemetic activity of domperidone proved to be better than that of metoclopramide. No side effects were observed in patients treated with domperidone.

Key concepts: Domperidone, Metoclopramide, Medicine, Antiemetic, Dopamine antagonist, Chemotherapy, Anesthesia, Placebo

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[Domperidone as an anti-emetic in antineoplastic chemotherapy]. — Research Paper | ScholarLens