[Analyze of the residue level of acrylic acid in cosmetics by ion chromatography method].

OBJECTIVE: To develop a method for acrylic acid analysis in cosmetics by ion chromatography. METHODS: Cosmetic samples were extracted by ultrasonic wave, then the separation was carried out on IonPac AS11-HC column (4 mm x 250 mm I. D.) with 30 mmol/L KOH as the eluent. The flow rate of the eluent was 0.8 ml/min. ASRS 300 4 - mm anion inhibitor and conductivity detector were used. Standard curve method was used for quantitative analysis. RESULTS: The linear ranges of calibration curve was 1.16 - 46.4 mg/L for acrylic acid, r = 0. 9996. The limit of detection was 4.8 mg/kg. The recoveries of acrylic acid with three different base materials were 89.1% - 92.6%, 93.5% - 96.2% and 90.5% - 94.8%. The intra-day and the inter-day precision were 1.8% and 5.8%, respectively. CONCLUSION: The established ion chromatographic method was simple, speedy, sensitive, and can be used to analyze the residue level of acrylic acid in cosmetics.