ADVOCACY FOR A DEDICATED 70 MEV PROTON THERAPY FACILITY
A. Denker, Ch. Rethfeldt, J. Röhrich, Dino Cordini, Jens Heufelder, R. Stark, Andreas Weber
Abstract
A. Denker, Ch. Rethfeldt, J. Röhrich, Dino Cordini, Jens Heufelder, R. Stark, Andreas Weber
Abstract
Since 1998 we treated more then 1500 patients with eye tumours at the HZB cyclotron with a 68 MeV proton beam. The 5 years follow up shows a tumour control rate of more then 96%. The combination of a CT/MRT based planning and excellent physical beam conditions like 2 nA in the scattered proton beam, a 0.94 mm distal dose falloff and a dose penumbra of 2.1 mm offers the opportunity to keep side effects on a lowest level. However all new medical proton facilities are equipped with accelerators delivering beams of 230 MeV and more. While this is needed for deep seated tumours, a lot of physical and medical compromises have to be accepted for the treatment of shallow seated tumours like eye melanomas. Hence, we suggest a 70 MeV proton therapy facility. It should be equipped with a horizontal beam line and can have optionally a vertical line for more complicated cases under anaesthetics or for biological experiments. By the use of PBO-Lab and MCNPX beam line concepts and a radio-protecting architecture are designed.
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Since 1998 we treated more then 1500 patients with eye tumours at the HZB cyclotron with a 68 MeV proton beam. The 5 years follow up shows a tumour control rate of more then 96%. The combination of a CT/MRT based planning and excellent physical beam conditions like 2 nA in the scattered proton beam, a 0.94 mm distal dose falloff and a dose penumbra of 2.1 mm offers the opportunity to keep side effects on a lowest level. However all new medical proton facilities are equipped with accelerators delivering beams of 230 MeV and more. While this is needed for deep seated tumours, a lot of physical and medical compromises have to be accepted for the treatment of shallow seated tumours like eye melanomas. Hence, we suggest a 70 MeV proton therapy facility. It should be equipped with a horizontal beam line and can have optionally a vertical line for more complicated cases under anaesthetics or for biological experiments. By the use of PBO-Lab and MCNPX beam line concepts and a radio-protecting architecture are designed.
Key concepts: Proton, Cyclotron, Beam (structure), Proton therapy, Beamline, Physics, Line (geometry), Nuclear medicine