1999•PubMedRequires access

[Intrahepatic cholestasis in pregnancy treated with ursodeoxycholic acid].

Lars Grønlund

Abstract

Intrahepatic cholestasis of pregnancy is characterized by pruritus and raised maternal aminotransferases and bile acid in serum. It is correlated to increased risk of meconium staining of amniotic fluid, stillbirth and premature labour. A case of treatment with ursodeoxycholic acid from 26. to 36. week gestation is described. Ursodeoxycholic acid is an effective treatment of intrahepatic cholestasis of pregnancy, but the effect seems to decrease after a period.

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Available abstract

Key concepts: Ursodeoxycholic acid, Cholestasis of pregnancy, Cholestasis, Bile acid, Amniotic fluid, Meconium, Pregnancy, Gestation