2012PubMedRequires access

[Haemophilus influenzae nasopharyngeal colonization in children].

Fortino Solórzano‐Santos, Marı́a Guadalupe Miranda-Novales, Blanca Leaños-Miranda, Laura Alicia Ortiz-Ocampo, Gabriela Echániz-Avilés, Gerardo del Carmen Palacios-Saucedo, Héctor Guiscafré-Gallardo

Open publisher page 5 citations

Abstract

OBJECTIVE: to determine frequency, serotypes, biotypes and susceptibility to eight antibiotics in Haemophilus influenzae nasopharyngeal isolates in children under five years old from Mexico City. METHODS: cross-sectional survey including children two months to five years old. A nasopharyngeal sample was taken. Haemophilus influenzae identification, serotyping, biotyping and antimicrobial susceptibility were performed. RESULTS: a sample of 573 children were included. In 88/573 (15.3 %) H. influenzae was isolated, corresponding in 7/573 (1.2 %) to Hib, 3/573 (0.5 %) to Hi a, c, d, f and 78/573 (13.6 %) to Nontypable Hi. Among Hib carriers, 6 had received only one or two doses of specific vaccine. Biotype VIII (76.1 %) was the predominant. All isolates were susceptible to the antibiotics, but one Hib strain was resistant to erithromycin. CONCLUSIONS: nontypable Haemophilus influenzae was predominant. Colonization by Hib in children under 5 years old was low (1.2 %), occurring in children with an incomplete vaccination schedule.

About this research paper

What this paper is about

OBJECTIVE: to determine frequency, serotypes, biotypes and susceptibility to eight antibiotics in Haemophilus influenzae nasopharyngeal isolates in children under five years old from Mexico City. METHODS: cross-sectional survey including children two months to five years old. A nasopharyngeal sample was taken. Haemophilus influenzae identification, serotyping, biotyping and antimicrobial susceptibility were performed. RESULTS: a sample of 573 children were included. In 88/573 (15.3 %) H. influenzae was isolated, corresponding in 7/573 (1.2 %) to Hib, 3/573 (0.5 %) to Hi a, c, d, f and 78/573 (13.6 %) to Nontypable Hi. Among Hib carriers, 6 had received only one or two doses of specific vaccine. Biotype VIII (76.1 %) was the predominant. All isolates were susceptible to the antibiotics, but one Hib strain was resistant to erithromycin. CONCLUSIONS: nontypable Haemophilus influenzae was predominant. Colonization by Hib in children under 5 years old was low (1.2 %), occurring in children with an incomplete vaccination schedule.

Why it matters

OpenAlex reports 5 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE: to determine frequency, serotypes, biotypes and susceptibility to eight antibiotics in Haemophilus influenzae nasopharyngeal isolates in children under five years old from Mexico City. METHODS: cross-sectional survey including children two months to five years old. A nasopharyngeal sample was taken. Haemophilus influenzae identification, serotyping, biotyping and antimicrobial susceptibility were performed. RESULTS: a sample of 573 children were included. In 88/573 (15.3 %) H. influenzae was isolated, corresponding in 7/573 (1.2 %) to Hib, 3/573 (0.5 %) to Hi a, c, d, f and 78/573 (13.6 %) to Nontypable Hi. Among Hib carriers, 6 had received only one or two doses of specific vaccine. Biotype VIII (76.1 %) was the predominant. All isolates were susceptible to the antibiotics, but one Hib strain was resistant to erithromycin. CONCLUSIONS: nontypable Haemophilus influenzae was predominant. Colonization by Hib in children under 5 years old was low (1.2 %), occurring in children with an incomplete vaccination schedule.

Key concepts: Haemophilus influenzae, Serotype, Pasteurellaceae, Hib vaccine, Microbiology, Colonization, Haemophilus, Antibiotics

Related papers

Back to paper searchBrowse research topicsOriginal source
[Haemophilus influenzae nasopharyngeal colonization in children]. — Research Paper | ScholarLens