Antithrombin III, Protein C and Protein S Plasma Levels in Patients with Behçet's Disease
Meliha Nalçacı, Yüksel Pekçelen
Abstract
Meliha Nalçacı, Yüksel Pekçelen
Abstract
The association between natural inhibitors of coagulation and thrombophilia was investigated in 35 patients with Behcet's disease. Antithrombin III and protein C levels were measured using synthetic chromogenic substrate methods, and protein S levels by quantitative enzyme-linked immunosorbent assay. There were no significant differences between patients and controls in plasma antithrombin III, protein C and free protein S concentrations. We conclude that there was no evidence of a primary coagulation inhibitor abnormality in patients with Behçet's disease.
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The association between natural inhibitors of coagulation and thrombophilia was investigated in 35 patients with Behcet's disease. Antithrombin III and protein C levels were measured using synthetic chromogenic substrate methods, and protein S levels by quantitative enzyme-linked immunosorbent assay. There were no significant differences between patients and controls in plasma antithrombin III, protein C and free protein S concentrations. We conclude that there was no evidence of a primary coagulation inhibitor abnormality in patients with Behçet's disease.
Key concepts: Antithrombin, Medicine, Protein S, Protein C, Behcet's disease, Coagulation, Thrombophilia, Internal medicine