2015PubMedRequires access

Central giant cell granuloma located in the maxilla in a 8-year old boy.

Anna Janas‐Naze, Piotr Osica

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Abstract

UNLABELLED: Central giant cell granuloma is a rare occurring tumor-like lesion of the facial part of the skull, located more often in mandible (from 2:1 to 3:1), than in the maxilla. It accounts for 7% of all benign tumors of the jaws, whereas the brown tumor is a complication of a primary hyperparathyroidism and occurs in approximately 4.5%, or in 1.5%, when the tumor is a complication of secondary hyperparathyroidism. However, the brown tumor is significantly less often observed than the presented lesion. The authors describe a case of central giant cell granuloma of the maxilla, located in the area of premolar teeth. Pantomograhic x ray showed unilocular osteolytic bone loss of the maxilla with ectopic teeth. As a part of the One Day surgery procedures, the tumor has been removed with the margin and embedded teeth, and oroantral communication closure performed. In follow-up examination after 10 months and 2 years from the surgery, no recurrence of the tumor has been observed. CONCLUSION: In diferential diagnosis of tumors of face and skull, it is needed to consider the giant cell granuloma and also the brown bone tumor.

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What this paper is about

UNLABELLED: Central giant cell granuloma is a rare occurring tumor-like lesion of the facial part of the skull, located more often in mandible (from 2:1 to 3:1), than in the maxilla. It accounts for 7% of all benign tumors of the jaws, whereas the brown tumor is a complication of a primary hyperparathyroidism and occurs in approximately 4.5%, or in 1.5%, when the tumor is a complication of secondary hyperparathyroidism. However, the brown tumor is significantly less often observed than the presented lesion. The authors describe a case of central giant cell granuloma of the maxilla, located in the area of premolar teeth. Pantomograhic x ray showed unilocular osteolytic bone loss of the maxilla with ectopic teeth. As a part of the One Day surgery procedures, the tumor has been removed with the margin and embedded teeth, and oroantral communication closure performed. In follow-up examination after 10 months and 2 years from the surgery, no recurrence of the tumor has been observed. CONCLUSION: In diferential diagnosis of tumors of face and skull, it is needed to consider the giant cell granuloma and also the brown bone tumor.

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Available abstract

UNLABELLED: Central giant cell granuloma is a rare occurring tumor-like lesion of the facial part of the skull, located more often in mandible (from 2:1 to 3:1), than in the maxilla. It accounts for 7% of all benign tumors of the jaws, whereas the brown tumor is a complication of a primary hyperparathyroidism and occurs in approximately 4.5%, or in 1.5%, when the tumor is a complication of secondary hyperparathyroidism. However, the brown tumor is significantly less often observed than the presented lesion. The authors describe a case of central giant cell granuloma of the maxilla, located in the area of premolar teeth. Pantomograhic x ray showed unilocular osteolytic bone loss of the maxilla with ectopic teeth. As a part of the One Day surgery procedures, the tumor has been removed with the margin and embedded teeth, and oroantral communication closure performed. In follow-up examination after 10 months and 2 years from the surgery, no recurrence of the tumor has been observed. CONCLUSION: In diferential diagnosis of tumors of face and skull, it is needed to consider the giant cell granuloma and also the brown bone tumor.

Key concepts: Medicine, Central giant-cell granuloma, Brown tumor, Maxilla, Skull, Mandible (arthropod mouthpart), Giant cell, Lesion

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