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Total body irradiation in the conditioning regimen for hematological malignancies.

V. Vitale, Salvina Barra, P. Franzone

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Abstract

The role of Total Body Irradiation (TBI) is well defined in the conditioning regimen for BMT, but in pediatric malignancies there are some particular points of discussion, due to the side effects of irradiation. As alternative methods have been described, as Busulfan based regimens, a critical balance between efficacy and toxicities has to be considered in this subset of patients.

About this research paper

What this paper is about

The role of Total Body Irradiation (TBI) is well defined in the conditioning regimen for BMT, but in pediatric malignancies there are some particular points of discussion, due to the side effects of irradiation. As alternative methods have been described, as Busulfan based regimens, a critical balance between efficacy and toxicities has to be considered in this subset of patients.

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OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

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Available abstract

The role of Total Body Irradiation (TBI) is well defined in the conditioning regimen for BMT, but in pediatric malignancies there are some particular points of discussion, due to the side effects of irradiation. As alternative methods have been described, as Busulfan based regimens, a critical balance between efficacy and toxicities has to be considered in this subset of patients.

Key concepts: Total body irradiation, Medicine, Conditioning regimen, Busulfan, Regimen, Conditioning, Oncology, Internal medicine

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Total body irradiation in the conditioning regimen for hematological malignancies. — Research Paper | ScholarLens