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[Measurement of liver volume and its clinical significance in cirrhotic patients].

Junming Zhu, Xiaoling Leng, Nan Dong, Gui Song Qi, Rongpin Du

Abstract

OBJECTIVE: To evaluate whether, preoperative measurement of liver volume is of value to the evaluation of tolerance to operation and long-term prognosis in cirrhotic patients with portal hypertension. METHODS: We assessed liver volume in 18 cirrhotics and 31 noncirrhotic controls with 3-dimensional shaded surface display by CT twin. RESULTS: The liver volume in controls was positively correlated to the height (r = 0.42, P < 0.05). The average of liver volume in controls was (1 070.68 +/- 227.52) cm(3) and was different from that of cirrhotics (797.02 +/- 135.11) cm(3) (P < 0.05). Liver volume of cirrhotic patients with portal hypertension was related to their Child classification. The liver volume of patients in Child C group was significantly smaller than that of patients of Child B group. CONCLUSIONS: The patients with smaller liver volume are likely complicated by encephalopathy after shunting procedure. However, the liver volume is not significantly correlated with portal blood flux and portosystemic shunt index.

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Key concepts: Medicine, Portal hypertension, Internal medicine, Gastroenterology, Hepatic encephalopathy, Portosystemic shunt, Cirrhosis, Volume (thermodynamics)