1974•PubMedRequires access

Decreased adhesion of platelets to subendothelium in von Willebrand's disease.

Thomas B. Tschopp, Harvey J. Weiss, Hans Rudolf Baumgartner

Abstract

Abstract The adhesion of platelets in flowing blood to the subendothelial surface of rabbit aorta was studied by a quantitative, in vitro method. Platelet adhension was significantly decreased in 5 patients with von Willebrand's disease. Impaired adhesion of platelets to some component of the blood vessel wall may account for the prolonged bleeding time in these patients.

About this research paper

What this paper is about

Why it matters

OpenAlex reports 384 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Key concepts: Platelet, Platelet adhesion, Adhesion, Platelet adhesiveness, Von Willebrand disease, Aorta, Chemistry, In vitro