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[Beta-adrenergic receptors in the cardiovascular system. The participation of propranolol insensitive beta-adrenoceptors in the regulation of the cardiovascular system].

Barbara Malinowska, Hanna Kozłowska, Agnieszka Zakrzeska, Grzegorz Kwolek

Abstract

In this paper we described the participation of beta-adrenoceptors in the regulation of the cardiovascular system. We characterized mainly the low-affinty state of beta1-adrenoceptors and beta3-adrenoceptors, which are insensitive to propranolol (the antagonist of beta1-/beta2-adrenoceptors). We also illustrated their function in the healthy and failing heart. In addition the vasodilatory effects of these receptors ligands were described.

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Available abstract

Key concepts: Propranolol, Adrenergic receptor, Medicine, BETA (programming language), Adrenergic beta-Antagonists, Receptor, Adrenergic, Antagonist