1992•PubMedRequires access
Effects of peripheral type benzodiazepine antagonist PK 11195 on the lipid-lowering activity of diazepam in albino rats.
B Cuparencu, J Horák
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Abstract
The i.p. administration of PK 11195, a peripheral type benzodiazepine receptor antagonist in a dose of 1 mg/kg/day antagonized the action of u.p. injection of diazepam (5 mg/kg/day, 5 days) on serum triglycerides. It seems that the effects of diazepam on serum lipids were due to the stimulation of the peripheral type benzodiazepine receptors.